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KMID : 0604520050310030227
Journal of the Society of Cosmetic Scientists of Korea
2005 Volume.31 No. 3 p.227 ~ p.235
Effect of Angelica^{(R)} against Skin Photo-aging
Jin Moo-Hyun

Lee Sang-Hwa
Kang Sang-Jin
Jeong Min-Hwan
Lim Young-Hee
Abstract
Skin aging is not a disease nor an abnormal phenomenon but a collection of degenerative changes with age, characterized by skin dryness, wrinkle formation, and loss of skin elasticity. The skin wrinkles are caused by either genetically predisposed factors or environmental factors such as UV irradiation or physical/chemical stimulus. The histological manifestations of wrinkles are changes in both amount and integrity of elastic and collagen fibers. Here we report the isolation and characterization of 3 active compounds, prangenidin, 8-hydroxybergapten, and xanthotoxol from Angelica dahurica root. The anti-wrinkle activities of these compounds were also investigated.
KEYWORD
Angelica dahurica root, photoaging, HAS gene expression, collagen synthesis
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