KMID : 0604520050310030227
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Journal of the Society of Cosmetic Scientists of Korea 2005 Volume.31 No. 3 p.227 ~ p.235
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Effect of Angelica^{(R)} against Skin Photo-aging
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Jin Moo-Hyun
Lee Sang-Hwa Kang Sang-Jin Jeong Min-Hwan Lim Young-Hee
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Abstract
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Skin aging is not a disease nor an abnormal phenomenon but a collection of degenerative changes with age, characterized by skin dryness, wrinkle formation, and loss of skin elasticity. The skin wrinkles are caused by either genetically predisposed factors or environmental factors such as UV irradiation or physical/chemical stimulus. The histological manifestations of wrinkles are changes in both amount and integrity of elastic and collagen fibers. Here we report the isolation and characterization of 3 active compounds, prangenidin, 8-hydroxybergapten, and xanthotoxol from Angelica dahurica root. The anti-wrinkle activities of these compounds were also investigated.
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KEYWORD
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Angelica dahurica root, photoaging, HAS gene expression, collagen synthesis
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